Speaker: Dr. Qu Lu, University Medical Center Göttingen (UMG)
Date and time: May 28, 15:00–16:00
Venue: Auditorium, Y Building
Host: Wolfgang Baumeister
Abstract:
Cell metabolism is a complex and dynamic system that governs the flow of energy and materials. One crucial component of this system is fatty acid synthesis (FAS), which predominantly occurs on the fatty acid synthase (FAS) enzyme. The metabolic regulation of FAS impacts not only cellular energy but also material production, including ATP, NADPH, fatty acids, membrane systems, and lipid cycles. Our research leverages state-of-the-art technologies such as cryo-electron tomography (Cryo-ET), cryo-electron microscopy (Cryo-EM), mass spectrometry, and light microscopy to gain a comprehensive understanding of FAS regulation.
I will introduce a research workflow that highlights the pivotal role of Cryo-ET as the primary investigative tool. I will walk through the steps involved in obtaining results using tools we have either developed or applied. Additionally, I will discuss the advantages and disadvantages of this workflow.
Biography:
2022-2024, Postdoc Research Fellow; University Medical Center Göttingen, Göttingen, Germany
2019-2022, Postdoc Research Fellow; Max-Planck-Institute of Biochemistry, Martinsried, Germany
2018-2019, Visiting Scholar; iHmuan Institute, ShanghaiTech University, Shanghai, China
2012-2018, Ph.D., Institute of Biophysics, Chinese Academy of Sciences Beijing; iHuman Institute, ShanghaiTech University, Shanghai, China