[SPST Seminar] New catalysts and methods for stereoselective C–C fragment couplings

ON2024-06-06TAG: ShanghaiTech UniversityCATEGORY: Lecture

Topic: New catalysts and methods for stereoselective C–C fragment couplings

Speaker: Associate Professor Simon J. Meek, Department of Chemistry, University of North Carolina at Chapel Hill (UNC)

Date and time: June 7, 11:00–12:00
Venue: Room 105, #5 Building of SPST
Host: Gao De-Wei

Abstract:

The need for reliable catalysts and methods for efficient and stereoselective formation of C-C bonds, and in particular reactions that generate quaternary carbon stereocenters, represents an important and difficult challenge in chemical synthesis. This lecture will focus on our recent progress in catalytic site- and stereoselective olefin and carbonyl coupling reactions. Through the choice of different metal-based catalysts and strategies, it will be demonstrated that practical and robust protocols have been developed with a range of simple organoboron reagents, which allow for efficient and stereoselective assembly of organic molecules.