The Cajal body (CB), one of the biological condensates in the nucleus, was identified over 100 years ago and is involved in forming ribonucleoproteins (RNPs), such as snRNPs/snoRNPs. In addition, CBs play an essential role in nonsense-mediated mRNA decay, RNAi-based gene silencing, viral infection, and stress response. Several human diseases are associated with mutations in genes encoding CB compo...

A delegation led by Magdalena Skipper, Editor-in-Chief of Nature, visited ShanghaiTech University on June 21. The group was warmly welcomed by Jiang Mianheng, the Founding President of the university.At the meeting, Jiang Mianheng provided a brief introduction to the development of ShanghaiTech, covering its history, student cultivation, academics and research, and international cooperation. He al...

Recently, Dædalus, the open access Journal of the American Academy of Arts and Sciences, published a commentary by Jiang Mianheng, Chair of the University Governing Board and Founding President of ShanghaiTech University, in its latest Spring 2024 issue. The article provides an in-depth elucidation of ShanghaiTech University’s educational philosophy, highlighting the significance of liberal ...

On the afternoon of June 7, a delegation from the University of Seville led by Julián Martínez, Vice-Rector for Research, visited ShanghaiTech University. Other two delegation members included José M. de la Rosa, IEEE Fellow and Director of the International Projects’ General Office, and Plácido González Martínez, Distinguished Research Fellow, School of Architecture.At the meeting, Vi...

Amyotrophic lateral sclerosis (ALS) is a severe neurodegenerative disease. Patients experience muscle weakness, paralysis, and atrophy due to the degeneration and death of both upper and lower motor neurons, eventually leading to breathing difficulties and death. Unfortunately, there is currently no effective treatment for this disease, and patients typically die within 3-5 years after diagnosis.&...

On the afternoon of June 13, the University Auditorium was filled with an audience numbering over 500 from both within and outside the university, gathered to welcome the distinguished speaker for the 18th ShanghaiTech Lecture—Sir Paul Nurse, the 2001 Nobel Prize Winner in Physiology or Medicine. Jiang Ge, Vice President of the university, hosted the event.Sir Paul Nurse is a renowned British gene...

Assistant Professor Zhang Yapei at the School of Entrepreneurship and Management (SEM) at ShanghaiTech, together with her coauthors, Assistant Professor Sylvain Catherine at Wharton School of the University of Pennsylvania, and Professor Paolo Sodini from the Stockholm School of Economics, has recently found new evidence on the importance of countercyclical income risk in explaining household...

May 31, 2024Dear members of the ShanghaiTech community,I am writing to announce that I am stepping down as the president of the University, for the reason that I have fulfilled my two-term presidency of 10 years and already joined the “70s generation” a few years ago. Since it has always been my belief that for ShanghaiTech’s robust future development, we need a younger generation of capable le...

Recently, ShanghaiTech University held a meeting to announce leadership changes. With the approval of the Shanghai Municipal People’s Government and the Chinese Academy of Sciences, Jiang Mianheng has been appointed as the Chair of the University Governing Board, and Feng Donglai has been appointed as the President of ShanghaiTech University.The decisions were announced by Wang Ping, Deputy ...

Recently, a team led by Professor Liu Zhi-Jie, Director of the iHuman Institute, and Assistant Professor Hua Tian at the School of Life Science and Technology (SLST), in collaboration with the teams from Shandong University, and Shanghai Ninth People’s Hospital affiliated to Shanghai Jiao Tong University School of Medicine, unveiled the complex interactions between bitter taste receptor...

On the afternoon of May 28, Vivien Quéma, President of Grenoble INP – UGA, and Lorena Anghel, Vice President for International Affairs, paid a visit to ShanghaiTech University. The French delegation was warmly received by Yin Jie, ShanghaiTech’s Executive Vice President and Provost, as well as Vice President Zhu Zhiyuan and Vice President Jiang Ge.Since the signing of the Letter of Intent in Aug...

Autophagy is a conserved eukaryotic cellular process that delivers protein aggregates, damaged organelles, and invaded pathogens to the lysosome for degradation. Reticulophagy is a specialized form of autophagy that selectively breaks down damaged or redundant endoplasmic reticulum (ER) using the autophagy-lysosome pathway, thus maintaining ER homeostasis and dynamic equilibrium. Reticulophagy rec...

Abiotic stresses such as drought, salinity, and extreme temperatures threaten global crop yields. For optimum crop productivity, plants must efficiently combat these stresses. Rapid accumulation of proline under stress is a key feature and primary defense strategy in plants. Arabidopsis thaliana pyrroline-5-carboxylate synthase (AtP5CS), involved in proline metabolism, serves as the rate...

Optical frequency comb, composed of discrete spectral lines, derives the name from its presenting a uniform and comb-like distribution of signals in the frequency domain. Frequency dimension has its significance as emphasized by Nobel laureate Arthur Schawlow’s quote, “Never measure anything but frequency”. The optical frequency comb significantly enhances the precision of freque...